Taking the non-road turbocharged inter-cooled diesel engine for research objects, by means of coupled fluid-solid analysis method, established the coupled heat transfer model of Cylinder head-Cooling fluid-Cylinder liner-Cylinder block,did a temperature test of flame face of cylinder head and key points of cylinder liner, studied the deformation of cylinder liner under the mechanical loads、thermal loads and coupled loads. The result show that temperature distribution of cylinder liner is not uniform, the highest temperature located in the top of the first cylinder liner; The deformation is relatively small under mechanical loads and the maximum value appeared in the thrust side of the top of the forth cylinder liner; The deformation is heart-shaped under coupled loads, the maximum value appeared in the top of the forth cylinder liner and close to the direction of flywheel, the thermal loads are predominant.