As the static implicit Finite Element Method（ FEM） is hard to simulate the wheels radial fatigue test accurately,this paper studies the simulated method with dynamic explicit FEM. It introduces the setting method of finite element,material performance parameter,tire,bolt pretention,weld,rotary drum,radial force,etc. It shown the distribution of stress and surface pressure of wheels,put forward a method to judge analysis result reasonable or not,and introduces the selection method of S-N curve for fatigue analysis. By comparing the FEA and test result,it knows that the dynamic explicit FEM setting method in this paper can get an idea analysis result.