Study on mechanical and permeability property of gradient multi-porous scaffold based on triply periodic minimal surface

QIN Shikun; DUAN Mingde; LIANG Shijie; ZHANG Hui; ZHANG Zhuangya

doi:DOI：10.16579/j.issn.1001.9669.2025.03.006

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Study on mechanical and permeability property of gradient multi-porous scaffold based on triply periodic minimal surface

·Experimental Research·Testing Technology· | 更新时间：2025-04-03

- Study on mechanical and permeability property of gradient multi-porous scaffold based on triply periodic minimal surface
- Journal of Mechanical Strength Vol. 47, Issue 3, Pages: 51-59(2025)
- 作者机构：
  
  河南科技大学机电工程学院，洛阳 471003
- 作者简介：
  
  DUAN Mingde, E-mail: duan_mingde@163.com
- 基金信息：
  
  Henan Province Key Science and Technology Research Project(212102210064);Joint Fund of Science and Technology Research and Development Plan of Henan Provincial(222103810030);Key Research Projects of Higher Education Institutions of Henan Province(20A460012)
- DOI：DOI：10.16579/j.issn.1001.9669.2025.03.006
  CLC：
- Received：06 July 2023，
  
  Revised：06 August 2023，
  
  Published：15 March 2025
- 稿件说明：
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秦世坤，段明德，梁士杰，等. 基于三周期极小曲面的梯度多孔支架力学及渗透性能研究［J］. 机械强度，2025，47（3）：51-59.

QIN Shikun，DUAN Mingde，LIANG Shijie，et al. Study on mechanical and permeability property of gradient multi-porous scaffold based on triply periodic minimal surfaces［J］. Journal of Mechanical Strength，2025，47（3）：51-59.
秦世坤，段明德，梁士杰，等. 基于三周期极小曲面的梯度多孔支架力学及渗透性能研究［J］. 机械强度，2025，47（3）：51-59. DOI： DOI：10.16579/j.issn.1001.9669.2025.03.006.

QIN Shikun，DUAN Mingde，LIANG Shijie，et al. Study on mechanical and permeability property of gradient multi-porous scaffold based on triply periodic minimal surfaces［J］. Journal of Mechanical Strength，2025，47（3）：51-59. DOI： DOI：10.16579/j.issn.1001.9669.2025.03.006.

摘要

为构建具有良好生物学性能的骨支架结构，基于三周期极小曲面（Triply Periodic Minimal Surface

TPMS）设计不同孔隙率、单胞尺度下的P型、FRD型匀质多孔支架，以及P&FRD梯度多孔支架；并通过试验和有限元仿真的方法，探究单胞类型、孔隙率及单胞尺度对TPMS多孔支架力学和生物学性能的影响。研究结果表明，基于TPMS建立的匀质和梯度多孔支架内部孔道具有良好的连通性；多孔支架的力学性能随着孔隙率的增加而降低，但渗透性则随着孔隙率的增加而提高；增大单胞尺度可以明显提高多孔支架的渗透性；梯度多孔支架的渗透率还受渗流方向的影响；梯度多孔支架能综合各匀质单胞结构的性能特点，在支架不同区域表现出不同的力学和生物学性能，更接近人体骨骼的结构和生物学性能。

Abstract

In order to construct a bone scaffold structure with good biological properties

P-type

FRD-type homogeneous multi-porous scaffolds and P&FRD gradient multi-porous scaffolds with different porosities and unit cell scales were designed based on the triply periodic minimal surface（TPMS）.The effects of unit cell types

porosities and unit cell scales on the mechanical and biological properties of TPMS multi-porous scaffolds were investigated by tests and finite element simulation.The results show that the internal pores of homogeneous and gradient multi-porous scaffolds based on TPMS have good connectivity.The mechanical properties of multi-porous scaffolds decrease with the increase of porosity

but the permeability increases with the increase of porosity.Increasing the unit cell scale can significantly improve the permeability of multi-porous scaffolds.The permeability of the gradient multi-porous scaffold is also affected by the seepage direction.The gradient multi-porous scaffolds can synthesize the performance characteristics of each homogeneous unit cell structure

and show different mechanical and biological properties in different regions of the scaffold

which is closer to the structure and biological properties of human bone.

关键词

Keywords

references

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